Creatine / nutrient timing and cell volumization:
"Beyond solubility the timing of ingesting creatine may also allow an athlete to take less. The latest research on "Differential effects of training on the control of skeletal muscle perfusion" (Delp M., Med. Sci. Sport & Ex. Vol. 30, #3, pp. 361-374) indicate some potential advantages for uptake by type II muscle fibers while they are perfused with blood relative to high intensity workloads. Basically we are trying to get the creatine into the blood while the metabolic window for uptake by the target muscle fiber (type II, fast twitch) is open, while the fiber is perfused with blood."
"Beyond solubility the timing of ingesting creatine may also allow an athlete to take less. The latest research on "Differential effects of training on the control of skeletal muscle perfusion" (Delp M., Med. Sci. Sport & Ex. Vol. 30, #3, pp. 361-374) indicate some potential advantages for uptake by type II muscle fibers while they are perfused with blood relative to high intensity workloads. Basically we are trying to get the creatine into the blood while the metabolic window for uptake by the target muscle fiber (type II, fast twitch) is open, while the fiber is perfused with blood."
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