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Turmeric/Curcumin: Underrated Wonder Herb!

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  • Turmeric/Curcumin: Underrated Wonder Herb!

    Hey there,

    For those of you who don't know, Turmeric is a spice commonly used in asian/indian dishes, such as curry. Sold as an anti-oxidant supplement, this will be popular in the coming years, I imagine.

    Found on the life extension foundation site :



    Muscle regeneration

    Believe it or not, curcumin has something in it that repairs muscle better than anything presently known. Derived from the spice turmeric, curcumin speeds recovery without injections or side effects. Although the data is preliminary, it appears that when curcumin is taken orally, it has the ability to home in on injured muscle. Once there, it changes the biochemistry of baby muscle cells, causing them to grow faster and clump together quicker to create new tissue. According to the study, curcumin caused muscle cells to fuse together twice as fast as they ordinarily would.

    It’s not known exactly how curcumin works. Researchers do know, however, that curcumin suppresses a factor that influences growth factors. This factor, NF B (nuclear factor kappa B), plays a prominent role in immunity and cell growth. Immediately after muscle injury, the immune system dispatches cells to the area. Their job is to destroy old tissue and begin new construction. NF B is one of the lines of communication immune cells use to get things done. By influencing NF B, curcumin modulates the repair process.

    The regeneration of muscle is a complex phenomenon. Curcumin works in part by changing the arrival time and status of chemical messengers known as cytokines. Cytokines appear at the scene early on, and they have a powerful effect on inflammation and cell growth. A cytokine known as IL-6 (interleukin-6), for example, makes muscle cells multiply. Another one called TNF (tumor necrosis factor) keeps cells from growing up, developing. By suppressing one, and enhancing the other, curcumin can speed things up.

    The authors of the study believe that curcumin works by other mechanisms that probably involve growth factors, but this has not been proven yet. In other attempts to make muscles regenerate, researchers have tried injecting synthetic growth factors or transplanting myoblasts–all with limited success. Curcumin seems to be a much safer, more effective treatment–at least in the early stages. The effects of curcumin are felt early on–right after injury when the body first sends out the repair squads. So if you want to try curcumin for muscle regeneration, make sure you take it as soon as the injury occurs. The authors of the study predict that curcumin may be useful not only for accidental injuries or sports, but also to help repair surgical damage.

    Thaloor D, et al. 1999. Systemic administration of the NF- B inhibitor curcumin stimulates muscle regeneration after traumatic injury. Am J Physiol 277(2 pt 1):C320-29.

    Other things to expect with Curcumin:
    1) Helps repair damaged muscles
    2) Acts as an anti-Cancer agent (maybe)
    3) Cures stomach ailments
    4) helps cholesterol levels
    5) Lowers BP
    6) Treating Gynecomastia
    7) anti-inflammatory activity

  • #2
    more...
    Systemic administration of the NF-kappaB inhibitor curcumin stimulates muscle regeneration after traumatic injury.

    Thaloor D, Miller KJ, Gephart J, Mitchell PO, Pavlath GK.

    Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

    Skeletal muscle is often the site of tissue injury due to trauma, disease, developmental defects or surgery. Yet, to date, no effective treatment is available to stimulate the repair of skeletal muscle. We show that the kinetics and extent of muscle regeneration in vivo after trauma are greatly enhanced following systemic administration of curcumin, a pharmacological inhibitor of the transcription factor NF-kappaB. Biochemical and histological analyses indicate an effect of curcumin after only 4 days of daily intraperitoneal injection compared with controls that require >2 wk to restore normal tissue architecture. Curcumin can act directly on cultured muscle precursor cells to stimulate both cell proliferation and differentiation under appropriate conditions. Other pharmacological and genetic inhibitors of NF-kappaB also stimulate muscle differentiation in vitro. Inhibition of NF-kappaB-mediated transcription was confirmed using reporter gene assays. We conclude that NF-kappaB exerts a role in regulating myogenesis and that modulation of NF-kappaB activity within muscle tissue is beneficial for muscle repair. The striking effects of curcumin on myogenesis suggest therapeutic applications for treating muscle injuries.

    PMID: 10444409 [PubMed - indexed for MEDLINE]

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    • #3
      interesting news. gonna check if you can buy this stuff in pill powder form or just run down to india block

      and be like OMG GIMMIE HERBS

      make me big and strong like your guys

      (the joke is here- 99percent indians i know are toothpics)

      good advice anyway thx
      Current LOGS
      http://forum.bodybuilding.com/showth...8#post12694688
      http://forums.1fast400.com/?showtopi...0&#entry363619
      http://www.controlledlabsforum.com/s...2042#post42042

      Comment


      • #4
        You can buy it from BB.com in tablet form (You should look for a 95% extract) for cheap money - I got a bottle of 60 for $9.

        Comment


        • #5
          http://forum.bodybuilding.com/showthread.php?t=728713

          Comment


          • #6
            i just bought half a pound of this stuff on indian streeet in NYC

            sprinkled it into my eggs no diff in taste..

            ill be putting some into meals i im cooking if i remmeber
            Current LOGS
            http://forum.bodybuilding.com/showth...8#post12694688
            http://forums.1fast400.com/?showtopi...0&#entry363619
            http://www.controlledlabsforum.com/s...2042#post42042

            Comment


            • #7
              Dang, those people never knew what they had. Maybe I'll try it soon; my g/f is a hardcore fan of herbs.

              Comment


              • #8
                Originally posted by hypnotikk
                Dang, those people never knew what they had. Maybe I'll try it soon; my g/f is a hardcore fan of herbs.
                Excuse me?

                Ayurvedic Dr's are well aware of what it does. The same goes with the general population in most areas of Northern India, Pakistan etc.

                Comment


                • #9
                  I'm looking forward for one of you that is trying it to give us feedback =) That would be great.

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